Diet and Health FAQ

Tagged As: Humira And Crohns Disease

Question:
I'm very interested in this clinical trial for Humira. I've been following info on Adacolum for close to two years. Since I have Crohn's I am very interested in what the Adacolumn clinical trial I understand that you took part in utilized for evaluating your response to the treatment. And for inclusion in the clinical trial. I'm hearing for Crohn's they are using the assinine CDAI instead of good verification of response such as the sigmoidoscopy they used for UC evaluation. I get so disgusted w/these Crohn's clinical trials that use the CDAI for evaluating results of treatment.

Answer:
I've participated in two clinical trials thus far while attempting to bring my Crohn's into remission.  Adacolum Aphresis and Humira.  The Adacolum worked the best out of the two for me and what I appreciated the most was the no medication aspect!  It is somewhat down-time intensive as you are unable to use either of your arms during the treatment but the upside was loads more energy and a lot less pain - not to mention less trips to the bathroom and absolutely NO accidents after two weeks of treatment! It is my understanding that the CDAI is used because there are so many flavors of Crohn's Disease that affect the entire digestive tract as well as corresponding issues like arthritis, infections, adhesions, skin complications, etc. that there is no other method available at the present time to correctly measure a clinical remission point in a majority of patients.  While quite a lot of doctors use the SED rate to measure disease activity, my particular flavor of Crohn's Disease has proven time and again that SED rates can, at times, be quite meaningless to accurately measure disease activity.  Colonoscopy does not do it either as many of us have perfectly clear exams when the disease is active elsewhere.